SPURIOUS CAST.

\spjˈʊɹɪəs kˈast], \spjˈʊɹɪəs kˈast], \s_p_j_ˈʊ_ɹ_ɪ__ə_s k_ˈa_s_t]\

Definitions of SPURIOUS CAST.

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1920 - A practical medical dictionary.
By Stedman, Thomas Lathrop

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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