SPLEEN FOCUS FORMING VIRUSES
\splˈiːn fˈə͡ʊkəs fˈɔːmɪŋ vˈa͡ɪɹəsɪz], \splˈiːn fˈəʊkəs fˈɔːmɪŋ vˈaɪɹəsɪz], \s_p_l_ˈiː_n f_ˈəʊ_k_ə_s f_ˈɔː_m_ɪ_ŋ v_ˈaɪ_ɹ_ə_s_ɪ_z]\
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Strains of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with other viral types.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- splcuie plexus
- spleen
- spleen cancer
- spleen cancers
- spleen focus forming virus
- Spleen Focus Forming Viruses
- spleen neoplasm
- spleen neoplasms
- spleen-pulp
- spleen-wort
- spleened