\sfˈɛnɔ͡ɪdə͡l fˈɪʃə], \sfˈɛnɔ‍ɪdə‍l fˈɪʃə], \s_f_ˈɛ_n_ɔɪ_d_əl f_ˈɪ_ʃ_ə]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Sporadic Retinoblastoma

  • A malignant arising nuclear layer retina that is most primary eye in children. The tumor tends to occur early childhood or infancy present at birth. majority are sporadic, but condition may be transmitted as autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; visual loss represent common clinical characteristics this condition. (From DeVita et al., Cancer: Principles Practice Oncology, 5th ed, p2104)
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