SINCALIDE RECEPTORS
\sˈɪnkəlˌa͡ɪd ɹɪsˈɛptəz], \sˈɪnkəlˌaɪd ɹɪsˈɛptəz], \s_ˈɪ_n_k_ə_l_ˌaɪ_d ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell surface proteins that bind cholecystokinin (CCK) with high affinity and trigger intracellular changes influencing the behavior of cells. Cholecystokinin receptors are activated by gastrin as well as by CCK-4; CCK-8; and CCK-33. Activation of these receptors evokes secretion of amylase by pancreatic acinar cells, acid and pepsin by stomach mucosal cells, and contraction of the pylorus and gall bladder. The role of the widespread CCK receptors in the central nervous system is not well understood.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.