SIMONELLI'S TEST

\sˈɪmə͡ʊnə͡lˌiz tˈɛst], \sˈɪmə‍ʊnə‍lˌiz tˈɛst], \s_ˈɪ_m_əʊ_n_əl_ˌi_z t_ˈɛ_s_t]\

Definitions of SIMONELLI'S TEST

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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