SHWARTZMAN PHENOMENON
\ˌɛsˈe͡ɪt͡ʃwˈɔːtsmən fɪnˈɒmɪnən], \ˌɛsˈeɪtʃwˈɔːtsmən fɪnˈɒmɪnən], \ˌɛ_s_ˈeɪ_tʃ_w_ˈɔː_t_s_m_ə_n f_ɪ_n_ˈɒ_m_ɪ_n_ə_n]\
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A vasculitis, local or systemic, caused by a two-stage reaction in which a first encounter with endotoxin produces intravascular fibrin thrombi whose clearance results in reticuloendothelial blockade which prevents the clearance of thrombi caused by a second encounter with endotoxin, (or a variety of polyanions, glycogen or antigen/antibody complexes) resulting in tissue necrosis and/or hemorrhage. In pregnancy gram-negative septicemia during delivery or abortion may serve as the first or provocative encounter.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
Nearby Words
- shuvel
- shwa
- shwan pan
- shwan-pan
- shwanpan
- Shwartzman Phenomenon
- shwartzman reaction
- shy
- shy away from
- shy drager syndrome
- shy magee syndrome