SERUM AMYLOID A PROTEIN (SAA)
\sˈɛɹəm ˈamɪlˌɔ͡ɪd ɐ pɹˈə͡ʊtiːn ˌɛsˌe͡ɪˈe͡ɪ], \sˈɛɹəm ˈamɪlˌɔɪd ɐ pɹˈəʊtiːn ˌɛsˌeɪˈeɪ], \s_ˈɛ_ɹ_ə_m ˈa_m_ɪ_l_ˌɔɪ_d ɐ p_ɹ_ˈəʊ_t_iː_n__ ˌɛ_s_ˌeɪ_ˈeɪ]\
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A serum protein believed to be a circulating precursor to amyloid protein AA. It is present in low concentrations in normal sera, but found in much higher concentrations in sera of older persons and in patients with amyloidosis or with diseases known to predispose to amyloidosis. Very high levels of this protein have been reported during acute inflammatory episodes. Antisera to amyloid protein AA cross-react with protein SAA.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.