\skˈɒts], \skˈɒts], \s_k_ˈɒ_t_s]\
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of or relating to or characteristic of Scotland or its people or culture or its English dialect or Gaelic language; "Scots gaelic"; "the Scots community in New York"; "`Scottish' tends to be the more formal term as in `The Scottish Symphony' or `Scottish authors' or `Scottish mountains'"; "`Scotch' is in disfavor with Scottish people and is used primarily outside Scotland except in such frozen phrases as `Scotch broth' or `Scotch whiskey' or `Scotch plaid'"
By Princeton University
By William Dodge Lewis, Edgar Arthur Singer
By James Champlin Fernald
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- A chromosome disorder associated either with an extra 21 or effective trisomy for 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe MENTAL RETARDATION. Cardiac gastrointestinal malformations, marked increase in incidence of LEUKEMIA, early onset ALZHEIMER DISEASE are also this condition. Pathologic features development NEUROFIBRILLARY TANGLES neurons deposition AMYLOID BETA-PROTEIN, similar pathology DISEASE. (Menkes, Textbook Child Neurology, 5th ed, p213)