SALICYLAZOSULFAPYRIDINE
\sˈalɪsˌɪle͡ɪzˌɒsəlfˌapɪɹˌɪdiːn], \sˈalɪsˌɪleɪzˌɒsəlfˌapɪɹˌɪdiːn], \s_ˈa_l_ɪ_s_ˌɪ_l_eɪ_z_ˌɒ_s_ə_l_f_ˌa_p_ɪ_ɹ_ˌɪ_d_iː_n]\
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A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.