SADOPLON 75
\sˈadɒplən sˈɛvəntifˈa͡ɪv], \sˈadɒplən sˈɛvəntifˈaɪv], \s_ˈa_d_ɒ_p_l_ə_n s_ˈɛ_v_ə_n_t_i_f_ˈaɪ_v]\
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A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme glutathione reductase. It has mutagenic activity and may induce chromosomal aberrations.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.