S HYDROXYALKYL GLUTATHIONE LYASE
\ˈɛs hˈa͡ɪdɹəksɪˌalka͡ɪl ɡlˌuːtɐθˈa͡ɪ͡əni lˈa͡ɪe͡ɪs], \ˈɛs hˈaɪdɹəksɪˌalkaɪl ɡlˌuːtɐθˈaɪəni lˈaɪeɪs], \ˈɛ_s h_ˈaɪ_d_ɹ_ə_k_s_ɪ__ˌa_l_k_aɪ_l ɡ_l_ˌuː_t_ɐ_θ_ˈaɪə_n_i l_ˈaɪ_eɪ_s]\
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A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic radicals as well as epoxides and arene oxides to glutathione. Addition takes place at the sulfur atom. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite. EC 2.5.1.18.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.