\ˌɑːɹˈɛks sˈɪks θˈa͡ʊzənd ən twˈɛntinˈa͡ɪn ˈɛm], \ˌɑːɹˈɛks sˈɪks θˈaʊzənd ən twˈɛntinˈaɪn ˈɛm], \ˌɑː_ɹ_ˈɛ_k_s s_ˈɪ_k_s θ_ˈaʊ_z_ə_n_d ə_n t_w_ˈɛ_n_t_i_n_ˈaɪ_n ˈɛ_m]\
Definitions of RX6029M
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A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
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bcr v abl Oncogene
- Retrovirus-associated DNA sequences (abl) originally isolated from Abelson murine leukemia virus (Ab-MuLV). proto-oncogene abl (codes for a protein that member tyrosine kinase family. human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It activated by translocation to bcr 22 in chronic myelogenous leukemia.