RETINOIC ACID BINDING PROTEINS
\ɹˈɛtɪnˌə͡ʊɪk ˈasɪd bˈa͡ɪndɪŋ pɹˈə͡ʊtiːnz], \ɹˈɛtɪnˌəʊɪk ˈasɪd bˈaɪndɪŋ pɹˈəʊtiːnz], \ɹ_ˈɛ_t_ɪ_n_ˌəʊ_ɪ_k ˈa_s_ɪ_d b_ˈaɪ_n_d_ɪ_ŋ p_ɹ_ˈəʊ_t_iː_n_z]\
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Proteins in the nucleus or cytoplasm that specifically bind retinoic acid or retinol and trigger changes in the behavior of cells. Retinoic acid receptors, like steroid receptors, are ligand-activated transcription regulators. Several types have been recognized.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.