REPLICATION ORIGIN
\ɹˌɛplɪkˈe͡ɪʃən ˈɒɹɪd͡ʒˌɪn], \ɹˌɛplɪkˈeɪʃən ˈɒɹɪdʒˌɪn], \ɹ_ˌɛ_p_l_ɪ_k_ˈeɪ_ʃ_ə_n ˈɒ_ɹ_ɪ_dʒ_ˌɪ_n]\
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A unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.