REM BEHAVIOR DISORDER
\ˌɑːɹˌiːˈɛm bɪhˈe͡ɪvjə dɪsˈɔːdə], \ˌɑːɹˌiːˈɛm bɪhˈeɪvjə dɪsˈɔːdə], \ˌɑː_ɹ_ˌiː__ˈɛ_m b_ɪ_h_ˈeɪ_v_j_ə d_ɪ_s_ˈɔː_d_ə]\
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A disorder characterized by episodes of vigorous and often violent motor activity during REM sleep (SLEEP, REM). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.