RECUPERATED
\ɹɪkjˈuːpəɹˌe͡ɪtɪd], \ɹɪkjˈuːpəɹˌeɪtɪd], \ɹ_ɪ_k_j_ˈuː_p_ə_ɹ_ˌeɪ_t_ɪ_d]\
Definitions of RECUPERATED
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ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.