RECKLINGHAUSEN DISEASE, NERVE
\ɹˈɛklɪŋhˌɔːsən dɪzˈiːz], \ɹˈɛklɪŋhˌɔːsən dɪzˈiːz], \ɹ_ˈɛ_k_l_ɪ_ŋ_h_ˌɔː_s_ə_n d_ɪ_z_ˈiː_z]\
Definitions of RECKLINGHAUSEN DISEASE, NERVE
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An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic neural crest. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18)
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- An Italian lyric poet(1552-1637); born at Savona. Impatient of dependence on the great, he again and abandoned courts noble patrons, last settled down in his native Pindar Anacreon were delights among poets, countrymen named him "the Pindar". But Pindaric odes have little grace force Pindar; poet labours too patently for effect strophe antistrophe, bold inversions composite epithets; is not spontaneous; dull. Yet some songs after are models elegance grace. epic dramatic poems hardly rise above mediocrity. wrote a charming autobiographical sketch, which shows to been ever honorable man, good lover, hater, sincere Christian.