RB GENE PRODUCT
\ˌɑːbˈiː d͡ʒˈiːn pɹˈɒdʌkt], \ˌɑːbˈiː dʒˈiːn pɹˈɒdʌkt], \ˌɑː_b_ˈiː dʒ_ˈiː_n p_ɹ_ˈɒ_d_ʌ_k_t]\
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Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- razzle-dazzle
- razzmatazz
- rã´le
- rb
- rb gene
- Rb Gene Product
- rb genes
- rb protein
- rb1 gene product
- rbc
- rbc cash index