\ɹˈandɒlf], \ɹˈandɒlf], \ɹ_ˈa_n_d_ɒ_l_f]\
Definitions of RANDOLPH, JOHN
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of Roanoke (June 2, 1773-June 24, 1833), was a near relative of Edmund Randolph. He was educated at Princeton and Columbia, and in 1799 entered the National House of Representatives from Virginia. Though very young, he soon became a leader on the Democratic side. His strict constructionism, however, was of the most thorough-going stamp, and he was frequently at variance with Jefferson and other party chiefs. Randolph was renowned for an eloquent satire of a peculiarly bitter kind, whose effect was enhanced by his personal eccentricities. He was foremost in the conflict against the Yazoo frauds and the Embargo. He also opposed Madison and the War of 1812. His career in the House lasted until 1825, with a break from 1813 to 1815. From 1825 to 1827 he was U.S. Senator. He invented the epithet "dough-faces" for Northern sympathizers with slavery, and styled the union of Adams and Clay a "coalition between the blackleg and the Puritan," which remark led to a duel with Clay. President Jackson sent him in 1830 as U.S. Minister to Russia, but his stay abroad was brief. There are lives of Randolph by Garland and by Henry Adams.
By John Franklin Jameson
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- Preparations of pathogenic organisms or their derivatives made nontoxic and intended for active immunologic prophylaxis. They include deactivated toxins.