R 4263

\ˈɑː fˈɔː θˈa͡ʊzənd tˈuːhˈʌndɹədən sˈɪkstiθɹˈiː], \ˈɑː fˈɔː θˈa‍ʊzənd tˈuːhˈʌndɹədən sˈɪkstiθɹˈiː], \ˈɑː f_ˈɔː θ_ˈaʊ_z_ə_n_d t_ˈuː_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɪ_k_s_t_i_θ_ɹ_ˈiː]\

Definitions of R 4263

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2010 - Medical Dictionary Database
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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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