Definitions of r metHuG CSF

  1. A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes. Clinically it is effective in decreasing the incidence of febrile neutropenia in patients with non- myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of neutropenia and neutropenia- related clinical sequelae in patients with non- myeloid malignancies undergoing myeloblastive chemotherapy followed by BMT. It has also been used in AIDS patients with CMV retinitis being treated with GANCICLOVIR. ( Gelman CR, Rumack BH & Hess AJ ( eds): DRUGDEX( R) System. MICROMEDEX, Inc., Englewood, Colorado ( Edition expires 11/ 30/ 95))