PTDINS 3 KINASE
\pˌiːtˌiːdˈiː ˈɪnz θɹˈiː kˈɪne͡ɪs], \pˌiːtˌiːdˈiː ˈɪnz θɹˈiː kˈɪneɪs], \p_ˌiː_t_ˌiː_d_ˈiː_ ˈɪ_n_z θ_ɹ_ˈiː k_ˈɪ_n_eɪ_s]\
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An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V (D)J recombination and cell cycle checkpoints. EC 2.7.1.137.
By DataStellar Co., Ltd
