PROPRANOLOL
\pɹˈɒpɹɐnˌɒlɒl], \pɹˈɒpɹɐnˌɒlɒl], \p_ɹ_ˈɒ_p_ɹ_ɐ_n_ˌɒ_l_ɒ_l]\
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A widely used non-cardioselective beta-adrenergic antagonist. Propranolol is used in the treatment or prevention of many disorders including acute myocardial infarction, arrhythmias, angina pectoris, hypertension, hypertensive emergencies, hyperthyroidism, migraine, pheochromocytoma, menopause, and anxiety.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.