PROMOTORS (GENETICS)
\pɹəmˈə͡ʊtəz d͡ʒɛnˈɛtɪks], \pɹəmˈəʊtəz dʒɛnˈɛtɪks], \p_ɹ_ə_m_ˈəʊ_t_ə_z__ dʒ_ɛ_n_ˈɛ_t_ɪ_k_s]\
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DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.