PROLIFERATING CELL NUCLEAR ANTIGEN
\pɹəlˈɪfəɹˌe͡ɪtɪŋ sˈɛl njˈuːkli͡əɹ ˈantɪd͡ʒˌɛn], \pɹəlˈɪfəɹˌeɪtɪŋ sˈɛl njˈuːkliəɹ ˈantɪdʒˌɛn], \p_ɹ_ə_l_ˈɪ_f_ə_ɹ_ˌeɪ_t_ɪ_ŋ s_ˈɛ_l n_j_ˈuː_k_l_iə_ɹ ˈa_n_t_ɪ_dʒ_ˌɛ_n]\
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Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
By DataStellar Co., Ltd
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