PROGRESSIVE SUPRANUCLEAR PALSY
\pɹəɡɹˈɛsɪv sˈʌpɹɐnjˌuːkli͡ə pˈɔːlzi], \pɹəɡɹˈɛsɪv sˈʌpɹɐnjˌuːkliə pˈɔːlzi], \p_ɹ_ə_ɡ_ɹ_ˈɛ_s_ɪ_v s_ˈʌ_p_ɹ_ɐ_n_j_ˌuː_k_l_iə p_ˈɔː_l_z_i]\
Sort: Oldest first
-
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- progressive relapsing multiple sclerosis
- progressive rock
- progressive supranuclear ophthalmoplegia
- progressive supranuclear ophthalmoplegias
- progressive supranuclear palsies
- Progressive Supranuclear Palsy
- progressive tax
- progressive tense
- progressive thrombus
- progressive torsion spasm
- progressive torsion spasm of childhood