PROGESTERONE 21 HYDROXYLASE
\pɹə͡ʊd͡ʒˈɛstəɹˌə͡ʊn twˈɛntiwˈɒn hˈa͡ɪdɹəksˌɪle͡ɪs], \pɹəʊdʒˈɛstəɹˌəʊn twˈɛntiwˈɒn hˈaɪdɹəksˌɪleɪs], \p_ɹ_əʊ_dʒ_ˈɛ_s_t_ə_ɹ_ˌəʊ_n t_w_ˈɛ_n_t_i_w_ˈɒ_n h_ˈaɪ_d_ɹ_ə_k_s_ˌɪ_l_eɪ_s]\
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A steroid hydroxylase system found in adrenal cortex microsomes. It catalyzes the 21-hydroxylation of corticosteroids and shows a requirement for NADPH and molecular oxygen. Its deficiency is a cause of adrenogenital syndrome. EC 1.14.99.10.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.