PROCHOWNICKS DIET'S METHOD

\pɹˈɒt͡ʃa͡ʊnˌɪks dˈa͡ɪ͡əts mˈɛθəd], \pɹˈɒt‍ʃa‍ʊnˌɪks dˈa‍ɪ‍əts mˈɛθəd], \p_ɹ_ˈɒ_tʃ_aʊ_n_ˌɪ_k_s d_ˈaɪə_t_s m_ˈɛ_θ_ə_d]\

Definitions of PROCHOWNICKS DIET'S METHOD

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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