PRKM1 GENE PRODUCT
\pˌiːˌɑːkˌe͡ɪˈɛm wˈɒn d͡ʒˈiːn pɹˈɒdʌkt], \pˌiːˌɑːkˌeɪˈɛm wˈɒn dʒˈiːn pɹˈɒdʌkt], \p_ˌiː__ˌɑː_k_ˌeɪ_ˈɛ_m w_ˈɒ_n dʒ_ˈiː_n p_ɹ_ˈɒ_d_ʌ_k_t]\
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Extracellular signal-regulated kinase 2. A proline-directed serine/threonine kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to translocation into the nucleus and phosphorylation of certain transcription factors. p40 MAPK and p41 MAPK are isoforms. EC 2.7.10.-.
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