PREMATURE ATRIAL CONTRACTION
\pɹɪmət͡ʃˈʊ͡əɹ ˈatɹɪəl kəntɹˈakʃən], \pɹɪmətʃˈʊəɹ ˈatɹɪəl kəntɹˈakʃən], \p_ɹ_ɪ_m_ə_tʃ_ˈʊə_ɹ ˈa_t_ɹ_ɪ__ə_l k_ə_n_t_ɹ_ˈa_k_ʃ_ə_n]\
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Premature contractions of the heart arising from an ectopic atrial focus. With ventricular premature complexes, they represent one of the most common causes of irregular pulse. They are more apt to occur if there is atrial or conduction system disease such as left atrial enlargement in mitral stenosis. In community prospective studies, atrial premature complexes are not related to sudden death, as are ventricular premature beats in coronary disease. (From Stedman, 25th ed; Braunwald, Heart Disease, 4th ed, p679; Sokolow, et al., Clinical Cardiology, 5th ed, p472)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.