PRE-EXISTENT
\pɹˈiːɛɡzˈɪstənt], \pɹˈiːɛɡzˈɪstənt], \p_ɹ_ˈiː__ɛ_ɡ_z_ˈɪ_s_t_ə_n_t]\
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.