POSTPHLEBITIC SYNDROMES

\pˌə͡ʊstflɪbˈɪtɪk sˈɪndɹə͡ʊmz], \pˌə‍ʊstflɪbˈɪtɪk sˈɪndɹə‍ʊmz], \p_ˌəʊ_s_t_f_l_ɪ_b_ˈɪ_t_ɪ_k s_ˈɪ_n_d_ɹ_əʊ_m_z]\

Definitions of POSTPHLEBITIC SYNDROMES

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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