POLYGLUTAMATE FOLATES
\pˌɒlɪɡlˈuːtɐmˌe͡ɪt fˈɒle͡ɪts], \pˌɒlɪɡlˈuːtɐmˌeɪt fˈɒleɪts], \p_ˌɒ_l_ɪ_ɡ_l_ˈuː_t_ɐ_m_ˌeɪ_t f_ˈɒ_l_eɪ_t_s]\
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Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
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