POISONING, 1 METHYL 4 PHENYL 1,2,3,6 TETRAHYDROPYRIDINE
\pˈɔ͡ɪzənɪŋ], \pˈɔɪzənɪŋ], \p_ˈɔɪ_z_ə_n_ɪ_ŋ]\
Definitions of POISONING, 1 METHYL 4 PHENYL 1,2,3,6 TETRAHYDROPYRIDINE
Sort: Oldest first
A condition caused by the neurotoxin 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. MPTP causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36 (2):250-8)
By DataStellar Co., Ltd
Word of the day
- contrivance by which the dies used in screw-cutting are held. A contrivance to hold the dies for cutting screws.