PLEXIFORM SCHWANNOMATOSIS
\plˈɛksɪfˌɔːm ʃwˌanəmɐtˈə͡ʊsɪs], \plˈɛksɪfˌɔːm ʃwˌanəmɐtˈəʊsɪs], \p_l_ˈɛ_k_s_ɪ_f_ˌɔː_m ʃ_w_ˌa_n_ə_m_ɐ_t_ˈəʊ_s_ɪ_s]\
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A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)
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