PLASMA THROMBOPLASTIN COMPONENT
\plˈazmə θɹˈɒmbəplˌastɪn kəmpˈə͡ʊnənt], \plˈazmə θɹˈɒmbəplˌastɪn kəmpˈəʊnənt], \p_l_ˈa_z_m_ə θ_ɹ_ˈɒ_m_b_ə_p_l_ˌa_s_t_ɪ_n k_ə_m_p_ˈəʊ_n_ə_n_t]\
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Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.