PITTSBURGH, PA
\pˈɪtsbɜːɡ], \pˈɪtsbɜːɡ], \p_ˈɪ_t_s_b_ɜː_ɡ]\
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Dates its history as a town from 1764, when its first streets were laid out. Previous to this time it had been a military station under the name of Fort Pitt, and still earlier (1755-1758) was the scene of a struggle between England and France for its possession, the French having founded Fort Duquesne here in 1754. Pittsburgh was incorporated as a city in 1816. In 1845 it was visited by a disastrous conflagration in which $5,000,000 worth of property was consumed.
By John Franklin Jameson
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.