PI 3K ALPHA P85 SUBUNIT
\pˌiːˈa͡ɪ θɹˈiː kˈe͡ɪ ˈalfə pˈiː ˈe͡ɪtifˈa͡ɪv sˈʌbjuːnˌɪt], \pˌiːˈaɪ θɹˈiː kˈeɪ ˈalfə pˈiː ˈeɪtifˈaɪv sˈʌbjuːnˌɪt], \p_ˌiː__ˈaɪ θ_ɹ_ˈiː k_ˈeɪ ˈa_l_f_ə p_ˈiː_ ˈeɪ_t_i_f_ˈaɪ_v s_ˈʌ_b_j_uː_n_ˌɪ_t]\
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An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V (D)J recombination and cell cycle checkpoints. EC 2.7.1.137.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- phytozoons
- phyz
- phænogamous
- pi
- pi 3k
- PI 3K alpha P85 Subunit
- pi 3k isotype p110 gamma
- pi 4 kinase
- pi dikinase pyruvate
- pi glycan
- pi meson