PERIOPLE

\pˈi͡əɹɪˌɒpə͡l], \pˈi‍əɹɪˌɒpə‍l], \p_ˈiə_ɹ_ɪ__ˌɒ_p_əl]\

Definitions of PERIOPLE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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