PERINEURIOMAS
\pˌɛɹɪnjˌuːɹɪˈə͡ʊməz], \pˌɛɹɪnjˌuːɹɪˈəʊməz], \p_ˌɛ_ɹ_ɪ_n_j_ˌuː_ɹ_ɪ__ˈəʊ_m_ə_z]\
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Tumors arising from nerve sheaths formed by SCHWANN CELLS in the peripheral nervous system and by oligodendrocytes in the central nervous system. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEURILEMMOMA are relatively common tumors in this category.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.