PERENNIAL ELEMENTS OF BIZZOZERO

\pəɹˈɛnɪəl ˈɛlɪmənts ɒv bˌɪzəzˈe͡əɹə͡ʊ], \pəɹˈɛnɪəl ˈɛlɪmənts ɒv bˌɪzəzˈe‍əɹə‍ʊ], \p_ə_ɹ_ˈɛ_n_ɪ__ə_l ˈɛ_l_ɪ_m_ə_n_t_s ɒ_v b_ˌɪ_z_ə_z_ˈeə_ɹ_əʊ]\

Definitions of PERENNIAL ELEMENTS OF BIZZOZERO

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1920 - A practical medical dictionary.
By Stedman, Thomas Lathrop

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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