PASSIVE TRANSFER EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS
\pˈasɪv tɹˈansfɜːɹ ɛkspˌɛɹɪmˈɛntə͡l ˌɔːtə͡ʊɪmjˈuːn mˌa͡ɪɐsθˈiːni͡ə ɡɹˈavɪs], \pˈasɪv tɹˈansfɜːɹ ɛkspˌɛɹɪmˈɛntəl ˌɔːtəʊɪmjˈuːn mˌaɪɐsθˈiːniə ɡɹˈavɪs], \p_ˈa_s_ɪ_v t_ɹ_ˈa_n_s_f_ɜː_ɹ ɛ_k_s_p_ˌɛ_ɹ_ɪ_m_ˈɛ_n_t_əl ˌɔː_t_əʊ_ɪ_m_j_ˈuː_n m_ˌaɪ__ɐ_s_θ_ˈiː_n_iə ɡ_ɹ_ˈa_v_ɪ_s]\
Definitions of PASSIVE TRANSFER EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS
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Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
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Nearby Words
- passive resistance
- passive resister
- passive retention
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- Passive Transfer Experimental Autoimmune Myasthenia Gravis
- passive transfer of immunity
- passive transfer test
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