PASSED BOYS

\pˈast bˈɔ͡ɪz], \pˈast bˈɔ‍ɪz], \p_ˈa_s_t b_ˈɔɪ_z]\

Definitions of PASSED BOYS

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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