PANHYPOPITUITARISM
\pˈanhɪpˌɒpɪtjˌuːɪtəɹˌɪzəm], \pˈanhɪpˌɒpɪtjˌuːɪtəɹˌɪzəm], \p_ˈa_n_h_ɪ_p_ˌɒ_p_ɪ_t_j_ˌuː_ɪ_t_ə_ɹ_ˌɪ_z_ə_m]\
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Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.