PALAKTOGEN
\pˈalɐktəd͡ʒən], \pˈalɐktədʒən], \p_ˈa_l_ɐ_k_t_ə_dʒ_ə_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.