\pˈak sˈɪkstifˈa͡ɪv], \pˈak sˈɪkstifˈaɪv], \p_ˈa_k s_ˈɪ_k_s_t_i_f_ˈaɪ_v]\
Definitions of PAK65
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A protein serine/threonine kinase which is involved in cell transformation by polyoma virus and is connected to the expression of IGF2. The immunosuppressant rapamycin inhibits the activation of the kinase, leading to reduced translation of certain mRNAs and a decrease in protein synthesis. EC 2.7.10.-.
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Board of Admiralty
- organized by Continental Congress, October 28, 1779, from earlier more numerous Committee. consisted two members Congress five others and had charge of all naval marine affairs. It was abolished February 7, 1781, upon the creation Secretary Marine.