PACHYOTIA

\pˌat͡ʃɪˈə͡ʊʃə], \pˌat‍ʃɪˈə‍ʊʃə], \p_ˌa_tʃ_ɪ__ˈəʊ_ʃ_ə]\

Definitions of PACHYOTIA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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