P42 MAP KINASE
\pˈiː fˈɔːtitˈuː ˌɛmˌe͡ɪpˈiː kˈɪne͡ɪs], \pˈiː fˈɔːtitˈuː ˌɛmˌeɪpˈiː kˈɪneɪs], \p_ˈiː f_ˈɔː_t_i_t_ˈuː ˌɛ_m_ˌeɪ_p_ˈiː k_ˈɪ_n_eɪ_s]\
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Extracellular signal-regulated kinase 2. A proline-directed serine/threonine kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to translocation into the nucleus and phosphorylation of certain transcription factors. p40 MAPK and p41 MAPK are isoforms. EC 2.7.10.-.
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