P38 MEMBRANE PROTEIN, SYNAPTIC VESICLE
\pˈiː θˈɜːtiˈe͡ɪt mˈɛmbɹe͡ɪn pɹˈə͡ʊtiːn], \pˈiː θˈɜːtiˈeɪt mˈɛmbɹeɪn pɹˈəʊtiːn], \p_ˈiː θ_ˈɜː_t_i__ˈeɪ_t m_ˈɛ_m_b_ɹ_eɪ_n p_ɹ_ˈəʊ_t_iː_n]\
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A 38-kDa integral membrane glycoprotein of the presynaptic vesicles in neuron and neuroendocrine cells. It is expressed by a variety of normal and neoplastic neuroendocrine cells and is therefore used as an immunocytochemical marker for neuroendocrine differentiation in various tumors. In ALZHEIMER DISEASE and other dementing disorders, there is an important synapse loss due in part to a decrease of synaptophysin in the presynaptic vesicles.
By DataStellar Co., Ltd
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