P185(C NEU)
\pˈiː wˈɒnhˈʌndɹədən ˈe͡ɪtifˈa͡ɪv sˈiː njˈuː], \pˈiː wˈɒnhˈʌndɹədən ˈeɪtifˈaɪv sˈiː njˈuː], \p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n ˈeɪ_t_i_f_ˈaɪ_v__ s_ˈiː n_j_ˈuː]\
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A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. EC 2.7.11.-.
By DataStellar Co., Ltd
Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.